Full disclosure: I am not, have never been, and don't foresee myself becoming a Hulk fan. It isn't entirely his fault, though: I think it's difficult to make a superhero whose only power is their super strength into an interesting character. I wouldn't say it's impossible to pull off, and Hulk does do it well, but the cards are stacked against him.
My cards, anyway.
That said, it's hard to argue against a hero whose sheer strength enables them to do some pretty insane stuff. When you're able to leap across oceans and push tectonic plates around with your bare hands (both are actual things that I believe Hulk is on record of doing), I have some doubts that a man in a big robot suit is going to stop you. Still, Iron Man's Hulkbuster armor is pretty awesome, and hero versus hero battles are always good fun. And while I'm not the most up-to-date on which rumors are still in circulation about Avengers 2, I'd be pretty excited if the Hulkbuster made an appearance.